Published in September 1987
Physician and Surgeon specializing in Dentistry. Periodontist.
Piazza Repubblica 4, 09129 Cagliari, Italy.
tel ++39 070 498159, fax ++39 070 400164
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Key words
blood coagulation, fibrin, thrombin, tissucol

2. Having prepared the receiving bed by baring the periosteum and freeing it of all overlying muscle and connective tissue, having apically stabilized the mucous flap to the periosteum with single stitches, two drops of Tissucol with thrombin at a concentration of 4 I.U./ml are applied.

1. Insufficient adhering gum at 2.4 (the alveolar mucosa, due to its elastic structure and with only one layer of cells, is not suitable to act as marginal gum and provide the epithelial attachment for the tooth, to maintain the "seal" and to support chewing trauma.
3. The free graft is adapted. 4. Following light compression for eight minutes the graft has adapted.
5. Healing after three months: the adhering gum has increased but the graft has undergone severe contraction and its blending is not good; the glue may have been reabsorbed too slowly. The appearance of the graft following removal of the first pack was not the healthiest. This may be due to a too-intense action of the aprotinina which, by inhibiting local fibrinolysis, may have interfered with the tropism of the graft.
6. Insufficient gum adhering to the four lower incisors.
7. Free gingival graft with Tissucol prepared with thrombin at a concentration of 4 I.U./ml after diluting the aprotinina by 50% with water for injectable solutions in order to have faster reabsorption of the glue.
8. Blending of the graft is quite good.